जीपीएससी परीक्षा पूर्वतयारी

1. Administration of cortisol will lead to

A Neutropenia

B Eosinophilia

C Neutrophilia

D Lymphocytosis

E None of the above

Correct Answer C

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2. Which cytokine is considered the principal endogenous mediator responsible for fever during acute inflammation?

A IL-2

B IL-1

C IL-4

D IL-10

E None of the above

Correct Answer B

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3. In Hexose Mono Phosphate shunt, in the presence of Thiamine Pyrophosphate, Transketolase catalysis the transfer of

A C2 unit from ketose to aldose

B C2 unit from aldose to ketose

C C3 unit from ketose to aldose

D C3 unit from aldose to ketose

E None of the above

Correct Answer A

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4.Which statement regarding apoptosis is most accurate?

A It invariably produces intense inflammatory response

B It occurs only under pathological conditions

C Caspase activation is a central event in the apoptotic pathway

D Cellular swelling is the characteristic morphological feature

E None of the above

Correct Answer C

Marks 1

5.Which of the following processes is most directly responsible for the osmotic pressure difference between blood plasma and interstitial fluid?

A Active transport of sodium

B Diffusion of oxygen

C Filtration at the glomerulus

D Oncotic pressure due to plasma proteins

E None of the above

Correct Answer D

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6. During negative energy balance, which of the following biomolecule acts as source of energy for neuron?

A Fructose

B Oleic acid

C Glutamate

D Acetoacetate

E None of the above

Correct Answer D

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7. What is the primary role of aquaporins in the regulation of body fluids?

A Transporting glucose across cell membrane

B Facilitating movement of amino acids across the cell membrane

C Facilitating movement of water across the cell membrane

D Transporting ions across cell membrane

E None of the above

Correct Answer C

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8. Which phase of the cardiac cycle corresponds with closure of the atrioventricular valves and onset of ventricular systole?

A Ventricular filling

B Rapid ejection

C Isovolumetric contraction

D Isovolumetric relaxation

E None of the above

Correct Answer C

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9. Iron deficiency leads to anaemia which is

A Microcytic, normochromic

B Microcytic, hyperchromic

C Microcytic, hypochromic

D Macrocytic, hypochromic

E None of the above

Correct Answer C

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10. I n ruminants, excessive production of propionate in the rumen primarily favors which metabolic outcome in the liver? 4. In ruminants, excessive production of propionate in the rumen primarily favors

which metabolic outcome in the liver?

A Ketogenesis

B Lipogenesis

C Gluconeogenesis

D Ureagenesis

E None of the above

Correct Answer C

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11. Shock that occurs due to widespread vasodilation and decreased peripheral vascular resistance, is termed

A Cardiogenic shock

B Distributive shock

C Neurogenic shock

D Obstructive shock

E None of the above

Correct Answer B

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12. In erythrocytes, the pentose phosphate pathway is physiologically important primarily because it:

A Produces ATP required for Na+/K+ ATPase activity

B Generates ribose sugars for DNA synthesis

C Produces NADPH required for glutathione reduction

D Supplies acetyl-CoA for fatty acid synthesis

E None of the above

Correct Answer C

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13. The Genetic code for the 21st standard amino acid, Selenocysteine is

A ATG

B UGA

C UAG

D UAA

E None of the above

Correct Answer B

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14. When the hormones diffuse through interstitial fluid, the mode of transmission is termed as

A Exocrine

B Paracrine

C Endocrine

D Neurocrine

E None of the above

Correct Answer B

Marks 1

15. What is the primary mechanism by which the body compensates for respiratory acidosis?

A Increasing renal excretion of bicarbonate

B Increasing renal excretion of hydrogen ions

C Increasing production of erythropoietin

D Decreasing ventilation rate

E None of the above

Correct Answer B

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16. The part of nephron which helps in the formation of a gradient of osmotic pressure in the interstitial fluid of medulla of kidney is

A Loop of Henle

B Proximal Convoluted Tubule

C Distal Convoluted Tubule

D Collecting ducts

E None of the above

Correct Answer A

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17. The first antibody to appear in response to antigen and responsible for primary response

A IgA

B IgE

C IgG

D IgM

E None of the above

Correct Answer D

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18.Epididymal function depends on the stimulation by the hormone 

A Prostaglandin F₂ a

B Testosterone

C Estrogen

D Progesterone

E None of the above

Correct Answer B

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19. Which of the following best describes the role of the juxtaglomerular apparatus in the kidney?

A Filtering blood in the glomerulus

B Secreting Anti Diuretic Hormone (ADH)

C Sensing blood pressure and releasing renin

D Reabsorbing calcium ions in the distal tubule

E None of the above

Correct Answer C

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20. Which enzyme serves as the principal rate-limiting regulatory enzyme of glycolysis

A Hexokinase

B Pyruvate kinase

C Phosphofructokinase-1

D Glucose-6-phosphatase

E None of the above

Correct Answer C

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21. The partial pressure (mm Hg) of oxygen at the tissue level is

A 100

B 30 or less

C 104

D 40

E None of the above

Correct Answer B

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22.The main factor affecting sperm transport in female reproductive tract immediately after ejaculation is

A Uterine muscle contraction

B Sperm motility

C Endometrial crypts of uterus

D Presence of cervical mucus

E None of the above

Correct Answer A

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23. A deficiency of surfactant in neonatal animals primarily results in:

A Increased pulmonary compliance

B Collapse of alveoli during expiration

C Hypersecretion of mucus in bronchioles

D Increased oxygen affinity of hemoglobin

E None of the above

Correct Answer B

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24. During severe metabolic acidosis in ruminants, which renal adaptive mechanism contributes most directly to regeneration of bicarbonate ions?

A Increased sodium reabsorption in proximal tubule

B Increased secretion of potassium ions in distal tubule

C Enhanced ammoniagenesis from glutamine metabolism

D Increased passive diffusion of urea into medulla

E None of the above

Correct Answer C

Marks 1